KabuDo

NYSE: CRL · Life Sciences Tools & Services

Charles River Laboratories

Charles River is a contract research organization serving drug developers. It has three segments: Research Models and Services (purpose-bred rodents and other research models), Discovery and Safety Assessment (outsourced discovery and the non-clinical safety testing regulators require) and Manufacturing Solutions (microbial testing and biologics testing). 2025 revenue was $4.02 billion (−0.9%). Goodwill and intangible impairments produced a net loss of $144 million. Birgit Girshick became CEO in May 2026. The company has sold its CDMO and Cell Solutions businesses and some European discovery sites.

Last updated

Analysis last edited: October 14, 2026 · Financial data fetched: October 17, 2026 10:07 (SEC EDGAR) · Source 10-K filed: February 18, 2026

Built on10-K FY2025 · filed 2026-02-1810-Q (quarter ended 2026-09-26) · filed 2026-11-04

Next update expectedAfter FY2026’s 10-K is filed (roughly 60–90 days after fiscal year end (sooner for larger filers)), financials and analysis will be refreshed.

01

At a glanceFrom SEC data

Eight headline measures, each placed among the companies covered on this site.

Revenue growth
6.5%

Higher than 37% of 372 non-financial companies

Average yearly growth over the years shown

Operating margin
0.6%

Higher than 5% of 311 non-financial companies

Latest fiscal year (FY2025)

ROIC minus WACC
-8.3 pts

Higher than 7% of 311 non-financial companies

Return on capital above (or below) its estimated cost

Net debt ÷ EBITDA
4.5x

Higher than 84% of 304 non-financial companies

Below 0 means more cash than debt

Cash conversion
—

Operating cash flow ÷ net income

Dividend raises
—

Years the dividend per share rose, of the last 5

P/E today
416.4x

Latest close 2026-11-04; trailing 12 months to 2026-09-26

Beta
0.85

Above 1 = moves more than the market

Each marker shows where this company sits among the non-financial companies covered on this site, not all listed companies (left = lowest, right = highest). A high position is not automatically good — for net debt ÷ EBITDA, higher means more debt. Details and formulas are in the sections below and in How to read this.

02

Valuation todayFrom SEC data

Price-based measures at the latest close, next to the same measures at the last fiscal year-end.

Share price$340.01close on 2026-11-04

Market cap$16.73B

P/E today
416.4x

At FY2025 year-end: —

Earnings: trailing 12 months to 2026-09-26

P/B today
5.3x

At FY2025 year-end: 3.2x

Book value at FY2025 year-end

EV/EBITDA today
43.5x

At FY2025 year-end: 27.9x

EBITDA for FY2025

FCF yield today
3.1%

At FY2025 year-end: 5.2%

Free cash flow for FY2025

Dividend yield today
—

Dividends per share for FY2025

“Today” uses the latest closing price (2026-11-04, Yahoo Finance daily closing prices) and shares outstanding at the last fiscal year-end. The rest of this page — including the financial table and ROIC vs. WACC — uses fiscal year-end prices. These are reference figures, not a judgment of whether the stock is cheap or expensive.

03

What changed since last earningsFrom SEC data

The latest reported quarter against the same quarter a year earlier, the balance sheet against the previous quarter-end, and what management said in its latest earnings release.

Quarter ended Sep 26, 2026.

  • Revenue↓ −2.2%$1B → $983M (vs. a year earlier)
  • Operating margin↑ +7.3 pts13.3% → 20.6% (vs. a year earlier)
  • Net income↑ +512.0%$54M → $333M (vs. a year earlier)
  • Diluted EPS↑ +523.6%$1.10 → $6.86 (vs. a year earlier)
  • Cash↑ +4.4%$192M → $200M (vs. previous quarter-end)

Source: Form 10-Q ↗ (SEC XBRL). Long-term debt is the tagged long-term debt figure and leaves out short-term borrowings.

From the earnings release of Nov 4, 2026.

Management outlook ↑ Raised

Raised organic revenue guidance by 100 basis points and non-GAAP EPS guidance by $0.15 at the midpoint. Source sentence
Organic revenue guidance increasing by 100 basis points and non-GAAP earnings per share guidance increasing by $0.15 at midpoint.

Key changes

  • Q3 revenue $982.7M, down 2.2%. Source sentence
    Revenue was $982.7 million, a decrease of 2.2% from $1,004.9 million in the third quarter of 2025, primarily driven by the impact of the May 2026 divestitures.
  • Organic revenue up 4.7%. Source sentence
    On an organic basis, revenue increased 4.7%, driven by revenue growth in the Manufacturing Solutions (Manufacturing) and Discovery and Safety Assessment (DSA) segments.

Written by AI. A line appears only if its figures and direction match the quoted sentence, which an automatic check confirms. Companies' outlooks are their own and may not be met. Read the release ↗

04

Company profileFrom SEC dataShow

Legal name
CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
Headquarters
WILMINGTON, MA
Fiscal year end
12/27
Exchange & ticker
NYSE: CRL
Industry
Life Sciences Tools & Services
CIK
1100682

Workforce (as of FY2025 year-end)

  • Employees

    19,700

Source: Form 10-K (FY2025) cover page and business description

05

Earnings calendarFrom SEC dataShow

When the company reports each quarter: the quarter-end date, the day results were released, and when the 10-Q or 10-K was filed.

Next report

Q4 FY2026

Quarter end: December 2026. In past years, Q4 results were released 46–53 days after quarter end (Feb 18, 2026; Feb 19, 2025; Feb 14, 2024). No date has been announced in the sources this site uses.

Reporting pattern

  • Fiscal year ends around December 27.
  • Reports four times a year: three quarterly reports (10-Q) and an annual report (10-K) for Q4.
  • Earnings releases came 39–53 days after quarter end over the last 12 quarters.
QuarterQuarter endedEarnings release (8-K)Report filed (10-Q / 10-K)
Q3 FY2026Sep 26, 2026Nov 4, 2026 (+39 days)Nov 4, 2026 10-Q (+39 days)
Q2 FY2026Jun 27, 2026Aug 5, 2026 (+39 days)Aug 5, 2026 10-Q (+39 days)
Q1 FY2026Mar 28, 2026May 7, 2026 (+40 days)May 7, 2026 10-Q (+40 days)
Q4 FY2025Dec 27, 2025Feb 18, 2026 (+53 days)Feb 18, 2026 10-K (+53 days)
Q3 FY2025Sep 27, 2025Nov 5, 2025 (+39 days)Nov 5, 2025 10-Q (+39 days)
Q2 FY2025Jun 28, 2025Aug 6, 2025 (+39 days)Aug 6, 2025 10-Q (+39 days)
Q1 FY2025Mar 29, 2025May 7, 2025 (+39 days)May 7, 2025 10-Q (+39 days)
Q4 FY2024Dec 28, 2024Feb 19, 2025 (+53 days)Feb 19, 2025 10-K (+53 days)
Q3 FY2024Sep 28, 2024Nov 6, 2024 (+39 days)Nov 6, 2024 10-Q (+39 days)
Q2 FY2024Jun 29, 2024Aug 7, 2024 (+39 days)Aug 7, 2024 10-Q (+39 days)
Q1 FY2024Mar 30, 2024May 9, 2024 (+40 days)May 9, 2024 10-Q (+40 days)
Q4 FY2023Dec 30, 2023Feb 14, 2024 (+46 days)Feb 14, 2024 10-K (+46 days)

Source: SEC EDGAR filing history. Release dates are the dates the earnings release was furnished to the SEC on Form 8-K (Item 2.02), which is normally the day results are announced. For a quarter whose 10-Q or 10-K isn’t filed yet, the date is the latest Item 2.02 8-K since the previous report, which may be a preliminary or other results-related update. Fiscal years are labeled by the calendar year in which they end.

06

Flagship products & servicesSite analysis

  • RMS

    Research models

    Examples: Over 140 stocks and strains of purpose-bred rodents

    Also large research models and Insourcing Solutions.

  • DSA

    Safety assessment and discovery

    Examples: Toxicology, bioanalysis, in vitro testing

    Non-clinical studies required by regulators.

  • Manufacturing

    Microbial Solutions

    Examples: Endosafe

    Rapid quality-control testing, including lot-release testing for injectables.

Descriptions are from the FY2025 Form 10-K.

U.S., worldwide and country/regional share of flagship products/services

Only shares the company itself states (in its filings or press releases, sometimes citing a research firm) are shown. Scope and timing vary by figure — treat these as approximate.

  • Outsourced drug discovery, non-clinical development and safety testing

    Worldwide

    U.S. share

    —

    Not disclosed

    Worldwide share

    Largest provider

    Company-disclosed

    Per the 10-K; no percentage is given.

07

Recent strategic focusSite analysis

2025–2026 changes.

  1. CEO transition

    James Foster stepped down as CEO and Chairman, and COO Birgit Girshick became CEO on May 5, 2026. Glenn Coleman joined as CFO.

    Source: 8-Ks filed 2026-01-09 and 2026-02-18

  2. Divestitures

    In May 2026 Charles River completed the divestitures of its CDMO and Cell Solutions businesses and certain European Discovery Services sites.

    Source: Q2 2026 press release

  3. SEC inquiry closed

    On November 14, 2025, the SEC Division of Enforcement said it concluded its NHP-sourcing investigation and does not intend to recommend enforcement action.

    Source: 8-K filed 2025-11-17

  4. Investor Day

    In September 2026 the company outlined its Pathway to Purpose strategy and long-term targets through 2030, and reaffirmed 2026 guidance at the upper ends of the prior ranges.

    Source: Press release, 2026-09-24

Capex ÷ D&A (FY2025)

0.54x

Below depreciation — investment is being pared back

formulacapital expenditures ÷ depreciation & amortization

e.g.$219M ÷ $403M = 0.54x

termsCapital expenditures (capex) · Depreciation & amortization (D&A)

M&A spend (6-year total)

$2.2B

Latest year: $0

Cash-flow-statement spending on acquisitions, net of cash acquired

Where the money goes, over time

Unit: $M. Capex went from $167M in FY2020 to $219M in FY2025

  • Capex
  • M&A spend

formulacapital expenditures ÷ depreciation & amortization

termsCapital expenditures (capex) · Depreciation & amortization (D&A)

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

08

Key figures at a glanceFrom SEC data

FY2020–FY2025, 6 years.

Revenue (FY2025)

$4.02B

As reported in the 10-K

Revenue CAGR (5 years)

+6.5%▲favorable

formula(last-period revenue ÷ first-period revenue) ^ (1 ÷ years) − 1

e.g.($4,015M ÷ $2,924M) ^ (1÷5) − 1 = 6.5%

termsCAGR · ^ (exponent) · Revenue (net sales)

Operating margin (FY2025)

0.6%▼caution

-14.2pt vs. 5 years ago

formulaoperating income ÷ revenue × 100

e.g.$25M ÷ $4,015M × 100 = 0.6%

termsOperating income · Revenue (net sales)

ROE (FY2025)

-4.4%▼caution

6-year average: 10.4%

As reported in the 10-K

P/B (FY2025 end)

3.17x

formulafiscal year-end closing price ÷ book value per share

e.g.$203.66 ÷ $64.30 = 3.17x

termsP/B · BVPS

Period-end (fiscal year-end) value, not today's P/B

EV/EBITDA (FY2025 end)

27.9x

formula(market cap + interest-bearing debt − cash and equivalents) ÷ (operating income + depreciation & amortization)

e.g.($10,024M + $2,136M − $214M) ÷ ($25M + $403M) = 27.9x

termsEV/EBITDA · Market capitalization · Interest-bearing debt · EBITDA · Depreciation & amortization (D&A)

Period-end (fiscal year-end) value, not today's multiple

  • ▲

    Revenue grew +6.5% a year over 5 years (strong growth)

    From $2.92B in FY2020 to $4.02B in FY2025. The annualized rate (CAGR) makes it possible to compare growth pace across companies of different sizes.

  • ▼

    Operating margin declined: 14.8% → 0.6%

    How much operating profit is left per $100 of revenue. It moved -14.2 points over 5 years — pricing power, cost control, and product mix all show up here.

  • ―

    Equity ratio is 44.4% (a middling level)

    The share of total assets funded by equity rather than debt. 50%+ is often read as low bankruptcy risk, though the right level varies by industry (real estate and leasing run lower, for instance).

  • ▲

    Free cash flow was positive in 6 of 6 years

    Operating cash flow minus capital expenditures: the cash left over after funding the business’s own investment, available for dividends, buybacks, acquisitions, or debt paydown. A negative year can mean heavy investment, or weak core earnings — worth distinguishing.

  • ▲

    ROE averaged 10.4% over 6 years (latest: -4.4%)

    How much profit was generated on shareholders’ equity. Roughly 10%+ is often cited as solid for a U.S. company, though this varies a lot by industry and capital intensity.

09

Business modelSite analysis

Discovery and Safety Assessment (DSA)

Outsourced drug discovery and the non-clinical safety testing that regulators require for new drugs, vaccines, chemicals and devices.

Discovery and Safety Assessment (DSA): how money and goods flow
  1. 01 what it draws on

    Inputs & resources

    • Laboratories and scientists
    • Research models, including non-human primates
  2. 02 what it does

    Activities

    • Discovery services
    • Safety and toxicology studies
    • Bioanalysis
  3. 03 who it serves

    Customers

    • Large pharma, mid-size and emerging biotech
  4. 04 how money comes in

    How it earns

    • Study fees

Discovery and Safety Assessment (DSA): how it makes money

  • 2025 revenue $2.40B (−2.0%), operating income $425M.
  • The company raised its 2026 guidance partly on improving DSA demand.

Research Models and Services (RMS)

Production and sale of research models (over 140 stocks and strains of purpose-bred rodents) and related services such as insourcing solutions.

Research Models and Services (RMS): how money and goods flow
  1. 01 what it draws on

    Inputs & resources

    • Breeding facilities
  2. 02 what it does

    Activities

    • Producing research models
    • Colony management at client sites
  3. 03 who it serves

    Customers

    • Pharma, biotech, academia, government
  4. 04 how money comes in

    How it earns

    • Model sales and services

Research Models and Services (RMS): how it makes money

  • 2025 revenue $846M (+2.0%); operating income fell to $45M after a $102M intangible impairment.

Manufacturing Solutions

Microbial Solutions (rapid quality-control testing, such as Endosafe) and Biologics Solutions (testing of biologics).

Manufacturing Solutions: how money and goods flow
  1. 01 what it draws on

    Inputs & resources

    • Testing platforms
  2. 02 what it does

    Activities

    • Lot-release and quality-control testing
  3. 03 who it serves

    Customers

    • Drug manufacturers
  4. 04 how money comes in

    How it earns

    • Product and testing fees

Manufacturing Solutions: how it makes money

  • 2025 revenue $766M; operating loss of $184M, including a $165M goodwill impairment in Biologics Solutions.

Government & regulation around the business

Non-market factors from the company’s filings: what governments and regulators fund, buy, set, approve or restrict, and which part of the flow above each one touches.

Charles River is exposed to changes in trade, environmental and antitrust policy.

  • Trade & export rules

    Tariffs and trade rules

    Changes in trade policy, environmental regulation or antitrust enforcement could affect the business.

    Constrains the businessTouches: Inputs & resources

    Source: Form 10-K (FY2025)

Revenue by segment (FY2025)

Unit: $M — bar length = revenue, (%) = share of total company revenue, margin = segment profit ÷ segment revenue × 100

  • DSA

    2,402.9 (60%)

    profit 424.6 · margin 17.7%

  • RMS

    846.1 (21%)

    profit 44.6 · margin 5.3%

  • Manufacturing

    766.4 (19%)

    profit -184.3 · margin -24.0%

Source: Form 10-K (FY2025) — MD&A, segment results Profit is segment operating income; unallocated corporate costs were $259.7M.

10

Where it earnsSite analysis

Many U.S.-listed companies earn most of their revenue outside the U.S. — this breaks down revenue by country/region so it's clear where the business actually makes its money.

Largest market ()

U.S. — 53% of revenue

Revenue by country / region ()

Unit: — bar length = revenue, (%) = share of total company revenue

  • U.S.

    2,141.8 (53%)
  • Europe

    1,102.7 (27%)
  • Canada

    501 (12%)
  • Asia Pacific

    205 (5%)
  • Other

    64.9 (2%)

Source: Form 10-K (FY2025) — revenue by geographic area By location of the selling entity. Other covers Brazil, Israel and Mauritius.

11

Contract structureSite analysisShow

Short-term or spot sales carry different earnings quality than long-term or auto-renewing contracts — this shows how the company actually contracts with its customers.

12

Alliances & capital tiesSite analysisShow

Equity stakes, joint ventures, and strategic partnerships disclosed across the 10-K, 8-Ks, and proxy statement.

  • Business partnership

    Eli Lilly (TuneLab)

    Charles River joined Lilly's TuneLab AI/ML platform, providing non-clinical testing expertise.

    Source: Q2 2026 press release

13

Customers & suppliersSite analysis

Who the company sells to and buys from. Companies rarely name either, so named counterparties come only from the company's own filings and press releases; otherwise this lists the concentration figures the 10-K discloses.

Customers

Pharma and biotech companies, hospitals, academic institutions, government agencies and NGOs.

Named by the company

No client exceeded 4% of revenue.

Suppliers

Research model inputs, including non-human primates from audited and approved suppliers.

Named by the company

No supplier is named.

14

Competitors & peersSite analysis

Competitors the 10-K names, and the peer group the company itself chose in its proxy statement. Nothing here is this site's own pick.

The 10-K describes competitors including CROs, CDMOs, other service companies, universities and clients' internal departments, but does not name them.

Competitors named in the 10-K

Charles River's 10-K doesn't name competitors.

Peer group the company chose

2025 proxy peer group (37 companies), from the proxy statement. Peers are companies the board considers comparable — for example when setting executive pay — not necessarily direct competitors.

Used with survey data for a market composite benchmark. For 2026, Catalent is to be removed and Cooper Companies added.

Source: Proxy statement (DEF 14A, filed 2026-03-31) — peer group

Company names link to this site’s analysis where one exists; “site ↗” opens the company’s own website.

15

M&A historySite analysisShow

Companies acquired over the last five years, plus older large acquisitions that still anchor a current business — what each was bought to do, and what happened afterward. From the 10-K, 8-Ks, and the company's press releases.

Recent acquisitions are small and focused on supply and science.

Cash spent on acquisitions, FY2020–FY2025: $2.2B

  1. 2026-01

    Assets of K.F. (Cambodia) Ltd.

    Not stated

    Cambodia-based provider of non-human primates for research.

    Stated purpose (company)
    Vertically integrate DSA's NHP supply.

    Source: Form 10-K (FY2025) — Item 1

  2. 2026

    PathoQuest SAS

    Not stated

    Next Generation Sequencing services.

    Stated purpose (company)
    Not stated.

    Source: Q2 2026 press release

16

Six years of financialsFrom SEC data

Each chart's axis holds a single unit (never mixing dollars, %, and $/share). The table's per-period header links to the filing the numbers came from.

Revenue over time

Unit: $M

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Profit over time (operating → net)

Unit: $M

  • Operating income
  • Pretax income
  • Net income

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Margins over time

Unit: %

  • Operating margin
  • Net margin

formulaoperating income ÷ revenue × 100

termsOperating income · Revenue (net sales)

formulanet income attributable to the company ÷ revenue × 100

termsNet income (attributable to the company)

Cash flow over time

Unit: $M (below zero = cash went out)

  • Operating CF
  • Investing CF
  • Free CF

formulacash flow from operations − capital expenditures

termsFree cash flow (FCF) · Cash flow from operations (operating CF) · Capital expenditures (capex)

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Financial stability & capital efficiency

Unit: %

  • Equity ratio
  • ROE

formulatotal equity ÷ total assets × 100 (as reported in the 10-K)

termsStockholders’ equity · Total assets

formulanet income ÷ average equity (beginning + ending, ÷2) × 100 (as reported in the 10-K)

termsNet income (attributable to the company) · Stockholders’ equity

Earnings per share (EPS) and dividend per share

Unit: $

  • EPS

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Line itemFY202010-K on EDGAR ↗FY202110-K on EDGAR ↗FY202210-K on EDGAR ↗FY202310-K on EDGAR ↗FY202410-K on EDGAR ↗FY202510-K on EDGAR ↗
Income statement ($M)
Revenue2,9243,5403,9764,1294,0504,015
Operating income43359065161722725
Pretax income44748162358193-100
Net income (attributable)36439148647522-144
Revenue growthcalc(this year’s revenue − last year’s revenue) ÷ last year’s revenue × 100—21.1%12.3%3.9%-1.9%-0.9%
Operating margincalcoperating income ÷ revenue × 10014.8%16.7%16.4%14.9%5.6%0.6%
Net margincalcnet income attributable to the company ÷ revenue × 10012.5%11.0%12.2%11.5%0.5%-3.6%
Balance sheet ($M)
Total assets5,4917,0247,6038,1957,5287,135
Total equity2,1182,5392,9813,6023,4673,170
Interest-bearing debtSum of short- and long-term borrowings, notes/bonds payable1,9302,6642,7082,6472,2402,136
Equity ratio38.5%36.1%39.1%43.9%46.0%44.4%
ROE17.2%16.8%17.6%14.4%0.6%-4.4%
Cash flow ($M)
Operating CF547761620684735738
Investing CF-602-1,438-608-563-245-209
Financing CF47673-42-86-551-537
Free cash flowcalccash flow from operations − capital expenditures380532295365502518
Cash and equivalents228241234277195214
Per share & other
EPS ($)7.207.609.489.220.20-2.91
BVPS ($)42.4950.2158.4270.0667.6964.30
P/E (x)35.048.623.025.6930.8—
EV/EBITDA (x)calc(market cap + interest-bearing debt − cash and equivalents) ÷ (operating income + depreciation & amortization)21.324.614.215.619.627.9
P/B (x)calcfiscal year-end closing price ÷ book value per share5.927.353.733.372.753.17

P/B and EV/EBITDA use each period’s period-end (fiscal year-end) figures, not the current share price. Figures without a "calc" tag are as reported in the Form 10-K (the consolidated financial statements and, for older years, earlier 10-Ks), pulled automatically from SEC EDGAR. Where a later filing restated a prior period, the restated figure is used.

Last 8 quarters

Three-month figures from 10-Q filings. Change is versus the same quarter a year earlier. Newest quarter on top.

Quarter endedRevenueOperating incomeNet incomeDiluted EPS
2026-09-26$983M-2.2%$203M+51.4%$333M+512.0%$6.86
2026-06-27$1B-2.7%$120M+19.7%−$1M-102.8%$-0.03
2026-03-28$996M+1.2%$120M+60.6%−$15M-158.3%$-0.30
2025-12-27 †$994M-0.8%−$283M−$277M—
2025-09-27$1B$134M$54M$1.10
2025-06-28$1.03B$100M$52M$1.06
2025-03-29$984M$75M$25M$0.50
2024-12-28 †$1B−$168M−$214M—

† Fourth quarter = the 10-K’s annual figure minus the first three quarters; quarterly EPS isn’t derived this way because share counts change during the year.

17

Is ROIC above WACC?From SEC data

ROIC (the return on money invested in the business) above WACC (the cost of raising that money) means the company is creating value. WACC is an estimate, so its assumptions can be adjusted below.

ROIC (FY2025)

0.4%

formulaoperating income × (1 − tax rate) ÷ invested capital × 100 *invested capital = interest-bearing debt + total equity (average of beginning/ending)

e.g.$25M × (1 − 23%) ÷ $5,507M × 100 = 0.4%

termsOperating income · Effective tax rate · Invested capital · Interest-bearing debt · Total equity

WACC (this site’s estimate)

8.61%

formulacost of equity × equity weight + cost of debt × (1 − tax rate) × debt weight

e.g.Equity weight: $10.02B ÷ ($10.02B + $2.14B) = 82.4%

e.g.Debt weight: $2.14B ÷ ($10.02B + $2.14B) = 17.6%

e.g.WACC: 9.6% × 82.4% + 5.0% × (1 − 23%) × 17.6% = 8.61%

termsCost of equity · Equity weight (E/(D+E)) · Cost of debt · (1 − tax rate) · Debt weight (D/(D+E)) · Market capitalization

ROIC − WACC

-8.3pt▼caution

Falling short of the cost of capital (ROIC > WACC in only 2 of 6 years)

formulaROIC − WACC (positive means the business earns more than its cost of capital)

termsROIC · WACC

How firm is this? With the equity risk premium ±1 point and beta ±0.2, WACC runs 7.2%–10.4% and ROIC − WACC runs −10.0 to −6.8 points. The sign holds across this range. This describes the latest year and does not predict future value creation.

WACC 8.61% is this site’s estimate under the assumptions below (not a figure the company has published)

Risk-free rate
4.95% (10-year Treasury, 2026-11-03)
β
0.85 (price-derived adjusted beta, but correlation with the market is low (R² 0.05), so reliability is limited)
Equity risk premium
5.5%
Cost of equity
9.63%
Cost of debt
5.01%
Tax rate
23% (effective rate, FY2022–FY2024)
Capital structure (equity : debt)
82% : 18%
→ Change assumptions and recalculate

ROIC over time, vs. WACC

Unit: % — bars = each period's ROIC, horizontal line = latest WACC. Bars above the line are green, below are red

  • ROIC (above WACC)
  • ROIC (below WACC)
  • WACC 8.61%

formulaoperating income × (1 − tax rate) ÷ invested capital × 100 *invested capital = interest-bearing debt + total equity (average of beginning/ending)

termsOperating income · Effective tax rate · Invested capital · Interest-bearing debt · Total equity

formulacost of equity × equity weight + cost of debt × (1 − tax rate) × debt weight

termsCost of equity · Equity weight (E/(D+E)) · Cost of debt · (1 − tax rate) · Debt weight (D/(D+E)) · Market capitalization

Try different WACC assumptions

β and the equity risk premium are estimates with a real range of plausible values — move the sliders to check whether ROIC > WACC still holds. The risk-free rate starts at the 10-year Treasury yield on 2026-11-03 (U.S. Treasury).

Initial β: 0.85 (price-derived adjusted beta. Raw β 0.78, R² 0.05, 130 weeks)

formula0.67 × β + 0.33 (β = the slope of weekly stock returns regressed on weekly market returns)

e.g.0.67 × 0.775 + 0.33 = 0.850

termsβ (beta)

Period 2024-05-10–2026-11-04, using S&P 500 ETF (SPY) as the market proxy. Source: Yahoo Finance price history.

Cost of equity9.63%

formularisk-free rate + β × equity risk premium

e.g.5.0% + 0.85 × 5.5% = 9.6%

termsCAPM · Risk-free rate · β (beta) · Equity risk premium (market risk premium)

Market value of equity$10.02B

formulafiscal year-end closing price × shares outstanding (= market cap)

termsMarket capitalization · Market value of equity

Interest-bearing debt$2.14B
Cost of debt5.01%

formulainterest expense ÷ interest-bearing debt × 100 (clamped to 0–10%; falls back to the risk-free rate if there’s no debt)

termsInterest-bearing debt · Risk-free rate

Capital structure (equity weight : debt weight)82% : 18%

18

What the price implies (DCF)From SEC data

A company's value can be written as its free cash flow divided by (cost of capital − perpetual growth). Working that backwards from the market's valuation shows how much growth the share price assumed — compared here with the company's actual past growth.

Growth the price implies (price on 2026-11-04)

5.8%

Perpetual FCF growth: g = r − FCF ÷ EV = 8.6% − 2.8%

Past FCF growth (FY2020–FY2025)

+6.4%

Compound annual rate, 5 years

Past revenue growth (FY2020–FY2025)

+6.5%

Compound annual rate, 5 years

Inputs (FY2025): free cash flow $518M (operating CF − capex); enterprise value $18.66B = market cap $16.73B (latest close, 2026-11-04) + debt $2.14B − cash and short-term investments $214M; r = WACC of 8.6% using this page’s default assumptions (β 0.85, risk-free 5.0%, market premium 5.5%).

Three WACC scenarios

The same calculation under cautious, base and optimistic cost-of-capital assumptions (risk-free rate fixed at the 10-year Treasury yield). Pick one to load it into the sliders below.

Try your own assumptions

V = FCF ÷ (r − g). It starts at the implied growth rate, where the theoretical value equals today’s enterprise value.

Theoretical enterprise value

$18.52B

FCF $518M ÷ (8.6% − 5.8%)

Theoretical ÷ actual enterprise value

0.99x

Below 1x: these assumptions value the business below the market did

How sensitive the answer is

Theoretical ÷ actual enterprise value for each combination of r and g.

g \ r6.6%7.6%8.6%9.6%10.6%
0%0.42x0.37x0.32x0.29x0.26x
2%0.60x0.50x0.42x0.37x0.32x
4%1.07x0.77x0.60x0.50x0.42x
6%4.63x1.74x1.07x0.77x0.60x
8%——4.63x1.74x1.07x

A simplified model for seeing what the market price assumes, not a forecast or a target price. It treats free cash flow as growing at one constant rate forever; the result swings widely with small changes in r and g, and is undefined when g reaches r. Free cash flow here is operating cash flow minus capex, which is after interest — a full DCF of enterprise value would use cash flow before interest. Market cap uses the latest close (2026-11-04) × shares at fiscal year-end; free cash flow and WACC inputs are from the latest fiscal year.

19

Earnings qualityFrom SEC dataShow

The same reported profit can mean different things depending on whether it's backed by cash, driven by the core business, or the result of a one-off item. Four checks below.

  • ✓

    Operating CF ÷ net income: averages 7.85x

    Profit is backed by cash coming in.

  • ✓

    Accrual ratio (latest): -12.0%

    A small share of profit rests on accounting estimates.

  • ✓

    Days sales outstanding: 77 → 65 days

    No major slowdown in collecting on sales.

Operating CF vs. net income

Unit: $M — operating CF above net income means profit is backed by cash

  • Operating CF
  • Net income

formulacash flow from operations ÷ net income attributable to the company

termsCash flow from operations (operating CF) · Net income (attributable to the company)

formula(net income − operating CF) ÷ average total assets × 100

termsNet income (attributable to the company) · Cash flow from operations (operating CF) · Total assets

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Profit bridge (FY2025)

Unit: $M — what moved profit from operating income to net income

  • Profit (each stage)
  • Pushed profit up
  • Pushed profit down

formulaoperating income ÷ income before income taxes × 100

termsOperating income · Income before income taxes (pretax income)

Source: each period's Form 10-K (SEC EDGAR). Latest: filed 2026-02-18

Receivables & inventory days

Unit: days — days grow when receivables or inventory build up faster than sales

  • Days sales outstanding

formulaaverage receivables (opening + closing ÷ 2) ÷ revenue × 365

termsAccounts receivable · Revenue (net sales)

formulaaverage inventory (opening + closing ÷ 2) ÷ cost of revenue × 365

termsInventory · Cost of revenue (COGS)

Worked examples (latest period)

formulacash flow from operations ÷ net income attributable to the company

termsCash flow from operations (operating CF) · Net income (attributable to the company)

formulaoperating income ÷ income before income taxes × 100

termsOperating income · Income before income taxes (pretax income)

formulaaverage receivables (opening + closing ÷ 2) ÷ revenue × 365

e.g.($721M + $709M) ÷ 2 ÷ $4,015M × 365 = 65 days

termsAccounts receivable · Revenue (net sales)

formulaaverage inventory (opening + closing ÷ 2) ÷ cost of revenue × 365

termsInventory · Cost of revenue (COGS)

20

Who holds the sharesFrom SEC dataShow

How much of the stock large institutional investors report owning on SEC Form 13F, how much the directors and executive officers hold (and how much of the vote they control), and roughly how much is left for individual investors. Shown next to beta so the holder mix can be read alongside how much the stock swings.

Institutions, insiders and everyone else, 13F holdings as of 2026-06-30

“Everyone else” is what remains after shares reported on Form 13F and shares held by directors and executive officers: mostly individual investors, plus non-insider families or foundations and smaller or foreign institutions. The figures have different dates and 13F reports count some shares twice — read it as an approximate split.

Held by 13F filers
100%+

Reported total 119.1%

Directors & officers (shares)
1.3%
Everyone else (est.)
≈0%

individuals and other non-13F holders

Directors & officers (voting power)
1.3%

no separate voting figure; shown as shares

Institutional-ownership rank
2 of 416

1 = most institutional; 0% of covered companies have more

Beta (adjusted)
0.85

above 1 = swings more than the market

  • 56.8M shares reported by 569 13F filers ÷ 47.7M shares outstanding on 2026-07-25. Option positions are excluded.
  • The 13F total exceeds shares outstanding because some shares are reported twice — for example shares lent to short sellers and then bought by another manager, or holdings that overlapping managers both report.
  • Directors and executive officers as a group, from the proxy statement’s beneficial-ownership table; includes shares they can acquire within 60 days.
  • A large “everyone else” share can still reflect a family, trust or foundation stake held outside the board; check the proxy statement’s 5% holders.

Sources: SEC Form 13F data set (holdings as of 2026-06-30) · Form DEF 14A filed 2026-03-31 (beneficial ownership table) · Form 10-Q cover page (shares outstanding as of 2026-07-25)

21

Strengths & weaknessesSite analysis

Strengths

  1. 1. Broad client base

    No client exceeded 4% of revenue in 2025.

    Evidence: Form 10-K (FY2025) Item 1

  2. 2. Cash flow

    Operating cash flow was about $738M in 2025 despite the GAAP loss.

    Evidence: SEC EDGAR XBRL

  3. 3. Improving demand

    Q2 2026 organic growth of 0.1% was the highest since Q3 2023; the company raised its 2026 guidance.

    Evidence: Q2 2026 press release

Weaknesses

  1. 1. Impairments and losses

    Net income fell from $475M (2023) to $22M (2024) and a loss of $144M (2025).

    Evidence: SEC EDGAR XBRL

  2. 2. Revenue decline

    Revenue fell from $4.13B (2023) to $4.02B (2025).

    Evidence: Form 10-K (FY2025)

22

What draws investors to itSite analysis

Why the stock can look attractive to investors — each point paired with what has to hold for it to stay true, and the opposing view. This is this site's analysis, not a recommendation to buy or sell.

P/E (FY2025)

—

Price at fiscal year-end ÷ diluted EPS

Dividend yield (FY2025)

—

Dividends per share ÷ fiscal year-end price

Payout ratio (FY2025)

—

Dividends per share ÷ diluted EPS

FCF yield (FY2025)

5.2%

(Operating CF − capex) ÷ market cap

  1. 1. Recovery potential

    Organic growth turned positive in Q2 2026 and guidance was raised.

    What has to hold
    Biopharma R&D demand keeps improving.
    The other side
    GAAP results remain weak.

    Evidence: Q2 2026 press release

  2. 2. Buybacks

    Charles River repurchased $350M of stock in 2025 and $100M in Q2 2026.

    What has to hold
    Cash flow holds.
    The other side
    No dividend.

    Evidence: Form 10-K (FY2025); Q2 2026 press release

Charles River pays no dividend. The fiscal year ends on the last Saturday of December.

23

ResilienceSite analysisShow

How well the company could absorb a bad year: its financial buffer, how its revenue and profit held up in the worst year on record, and what the 10-K says about the business's exposure to shocks. Figures and filing statements only — no overall rating.

1. Financial buffer (FY2025)

Cash & short-term investments ÷ debt due within a year

100x+

$214M vs. $166,000

Interest coverage (operating income ÷ interest expense)

0.2x

$25M vs. $107M

Free cash flow ÷ dividends paid

—

2. Worst year in the record, and the recovery

FigureWorst year-over-year changeBack to the prior level?
Revenue-1.9% in FY2024 ($4.13B → $4.05B)Not yet, as of FY2025
Operating income-88.9% in FY2025 ($227M → $25M)Not yet, as of FY2025

Covers only the 6 fiscal years on record (FY2020–FY2025), which may not include a full recession — the worst year here isn’t necessarily how the company would fare in a severe downturn.

3. Business resilience (from the 10-K)

  • Diversified clients

    No client exceeded 8% of any segment's revenue.

    Source: Form 10-K (FY2025), Item 1

  • Cost actions

    The company reduced headcount by about 2% and is consolidating sites.

    Source: Form 10-K (FY2025), Human Capital

25

Risks (including geopolitical)Site analysis

Starting from the 10-K's Risk Factors section, organized by category — geopolitical, currency, raw materials, regulatory, disaster, and more — with impact and likelihood assessed by this site.

Risk map

Vertical = impact on results, horizontal = likelihood. Upper right = most severe. Numbers match the list below (placement is this site’s own assessment).

Impact
High
1
Med
34
2
Low
LowMedHigh

Likelihood →

"Company disclosure" vs. "this site’s assessment"

The description and mitigation for each risk are this site’s summary of the 10-K’s "Risk Factors" section. Impact and likelihood are this site’s own assessment, not the company’s — where the company discloses its own likelihood assessment, that is noted in the summary.

Impact is judged from how large the affected business is relative to total revenue/profit, and from the risk’s track record of moving results in the past. Likelihood is judged from the filing’s wording and the current business environment (already occurring, or recurring). See the rating criteria.

  1. 1Supply chain

    Non-human primate supply

    Company disclosure (summarized from the 10-K)
    Charles River depends on NHP availability and on procedures to ensure imported NHPs are purpose-bred. In January 2026 it bought assets of K.F. (Cambodia), an NHP supplier.
    Company’s stated mitigation
    Diversifying the NHP supply chain.
    This site’s assessment
    Impact High / Likelihood Med
  2. 2Demand & macro

    Biopharma spending

    Company disclosure (summarized from the 10-K)
    Client budget cuts and study cancellations reduce demand.
    Company’s stated mitigation
    Restructuring and cost actions.
    This site’s assessment
    Impact Med / Likelihood High
  3. 3Competition & technology shift

    Competition and alternatives

    Company disclosure (summarized from the 10-K)
    Charles River competes with CROs, CDMOs, universities and clients' in-house departments; competitors may develop superior technologies.
    Company’s stated mitigation
    Investment in in vitro and bioanalysis capabilities.
    This site’s assessment
    Impact Med / Likelihood Med
  4. 4Law & regulation

    Litigation

    Company disclosure (summarized from the 10-K)
    Securities class action and derivative suits relate to NHP sourcing. In November 2025 the SEC staff said it does not intend to recommend enforcement action.
    Company’s stated mitigation
    SEC investigation closed without enforcement recommendation.
    This site’s assessment
    Impact Med / Likelihood Med

26

What changed in the risk factorsFrom SEC data

Paragraphs in the latest 10-K's Risk Factors that have little overlap with the year before, and paragraphs that were dropped.

New or substantially reworded (8)

  • • Our review of potential strategic alternatives may not result in an executed or consummated transaction or other strategic alternative, and the process of reviewing strategic alternatives or the outcome could adversely affect our business.

  • We leverage software and hardware solutions from technology and services providers, including software-as-a-service and public cloud infrastructure, who have been subject to cybersecurity incidents in the past and may have incidents or breaches in the future. As of the date of this filing, to our knowledge, no prior cybersecurity incident or breach at a third party has had a material impact on our business. However, future incidents or breaches could cause us to suffer significant harm.

  • Uncertainties with respect to the development, deployment, and use of artificial intelligence present new risks and challenges and could adversely affect our business and reputation.

  • We, along with many businesses in the biopharmaceutical industry, are adopting and exploring the use of artificial intelligence (AI) in our business, and as an emerging and rapidly evolving technology, our use of AI introduces potential opportunities but also presents risks that could adversely affect our operations, information security and reputation. For example, algorithms may be flawed; data sets may be insufficient, of poor quality, or contain biased information; and inappropriate or controversial data practices by data scientists, engineers, and end-users could impair results. If the analyses that artificial intelligence-based applications assist in producing are deficient or inaccurate, we could be subjected to competitive harm, potential legal liability and brand or reputational harm. Use of AI-based software may also lead to cybersecurity risks or the release of confidential…

  • Our review of potential strategic alternatives may not result in an executed or consummated transaction or other strategic alternative, and the process of reviewing strategic alternatives or the outcome could adversely affect our business.

  • On May 6, 2025, in connection with a Cooperation Agreement entered into with a large shareholder of the Company, we agreed, among other things, to have the Strategic Planning and Capital Allocation Committee of our Board of Directors oversee and direct a comprehensive strategic review and evaluation of the Company’s business and prospects, including an examination of various alternatives to enhance long-term stockholder value. On November 5, 2025, the Company announced that, as part of our Board of Directors’ comprehensive strategic review of our business and growth prospects, we will focus on strategic initiatives to strengthen our leading scientific portfolio within our core markets through strategic acquisitions, partnerships, and internal investments; divest certain non-core assets; maximize our financial performance, including by implementing additional initiatives aimed at driving…

  • The process of reviewing potential strategic and operational alternatives is time consuming and costly and may divert management’s attention. Read more

    It may also be disruptive to our business operations and long-term planning, which may cause concern to our current or potential investors, customers, employees, strategic partners, vendors and other stakeholders and may have a material impact on our operating results or result in increased volatility in our stock price.

  • Any potential transaction or other strategic alternative, including, without limitation the acquisitions of the assets of K.F. Read more

    (Cambodia) Ltd. and Pathoquest SAS, would be dependent on a number of factors that may be beyond our control, including, among other things, market conditions, industry trends, regulatory approvals, and the availability of financing for a potential transaction on favorable terms. There can be no assurance that any potential transaction or other strategic alternative will be successfully implemented, achieve the intended benefits or provide greater value to our stockholders than that reflected in the current price of our common stock. Until the review process is concluded, perceived uncertainties related to our future may result in the loss of potential business opportunities, volatility in the market price of our common stock and difficulty attracting and…

7 more paragraphs differ; the filings below have the full text.

Matched automatically, quoted as filed, and may include rewording of an existing risk. Compares Item 1A of the 10-K filed Feb 18, 2026 ↗ with the 10-K filed Feb 19, 2025 ↗.

27

What to watch going forwardSite analysis

  • DSA demand and bookings.
  • NHP supply.
  • Progress on the Create the Future savings program (over $300M of cumulative savings expected for 2027–2030).
  • Portfolio divestitures.
  • Buybacks ($1.0B authorization from October 2025).

28

Source documentsShow

This page's financial figures come from the Form 10-Ks listed below. Check the original filings for full detail.

Last updated

Analysis last edited: October 14, 2026 · Financial data fetched: October 17, 2026 10:07 (SEC EDGAR) · Source 10-K filed: February 18, 2026

Built on10-K FY2025 · filed 2026-02-18

Next update expectedAfter FY2026’s 10-K is filed (roughly 60–90 days after fiscal year end (sooner for larger filers)), financials and analysis will be refreshed.

This page is this site’s own analysis based on public information, and does not represent Charles River Laboratories’s views. It is not a recommendation to buy or sell any security, and this site does not guarantee the accuracy of any figure or statement here. Always verify against the original source documents before making an investment decision.